Page 363 - 16Neonatal Jaundice_compressed
P. 363

Neonatal jaundice


 Bibliographic details   Study type &   Patient characteristics   Results   Reviewers Comments
 Evidence level
        Rh incompatibility: 0/6 (0%)

        G6PD deficiency: 1/6 (16.7%)

        Infection: 3/6 (50.0%)

        Idiopathic: 1/6 (16.7%)

 Author: Sgro M   Study type:   Diagnosis: Jaundice   Mean bilirubin levels
    Case series   Criteria: TSB ≥ 427 micromol/litre)   TSB: 464 ± 75 micromol/litre
 Year: 2006      Setting: Hospital
    Evidence level: 3      ABO incompatibility: 49/258 (18.9%)
 Country: Canada   Sample Size: 258
    Mean GA: 38.5 ± 1.4 weeks
 111
 Ref ID:     Rh incompatibility: Not reported
 Mean BW: 3360 ± 489 gms
 Gender M/F: 162/96   Incidence of G6PD deficiency: 20/258 (7.7%)

 Ethnicity: White 55.4%, Asian 24.3%, Aboriginal 7.6%,   Infection: 3/258 (1.2%)
 black 5.2%, Middle Eastern 4.0%, Latin American 2.8%
 Breastfeeding: Not reported
 Onset of Jaundice: Day 0 - 60   Idiopathic: Unclear

 Exclusion: None
 Author: Bjerre J   Study type:   Diagnosis: Jaundice   Mean bilirubin levels
    Case series   Criteria: TSB ≥ 445 micromol/litre   TSB: Not reported
 Year: 2008      Setting: Hospital
    Evidence level: 3      ABO incompatibility: 52/113 (46.0%)
 Country: Denmark   Sample Size: 113
    GA (range): 35 – 42 weeks   Rh incompatibility: 2/113 (0.2%)
 110
 Ref ID:     BW (range): 2380 - 4870gms
 Gender M/F: 69/44   Incidence of G6PD deficiency: 1/113 (0.9%)
 Ethnicity: Not reported
 Breastfeeding: Not reported   Infection: Not reported
 Onset of Jaundice: Day 0 - 28
        Idiopathic: Unclear
 Exclusion: None
 Author: Necheles T   Study type:   Diagnosis: Severe jaundice requiring exchange transfusions   Mean bilirubin levels   66 babies were in Greece and 9 were
    Case series   Criteria: Not reported   TSB: Not reported   in the USA
 Year: 1976      Setting: Hospital
    Evidence level: 3      ABO incompatibility: 29/75 (38.7%)
 Countries: United States &   Sample Size: 75
 Greece   GA: Not reported   Rh incompatibility: 6/75 (8.0%)
    BW: Not reported
 109
 Ref ID:     Gender M/F: 69/44   Incidence of G6PD deficiency: 14/75 (18.7%)
 Ethnicity: Not reported
 Breastfeeding: Not reported   Kernicterus
 Onset of Jaundice: Not reported   ABO incompatibility: 1/6 (16.7%)



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