Page 360 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic details Study type & Patient characteristics Results Reviewers Comments
Evidence level
Infection: 2/14 (14.3%)

Idiopathic: 1/14 (7.1%)
Author: Katar S Study type: Diagnosis: Jaundice Mean bilirubin levels Small study
Case series Criteria: TSB > 342 micromol/litre at 24–48 hours or TSB: 598 ± 185 micromol/litre
Year: 2008 ≥ 427 micromol/litre) at > 48 hours after birth
Evidence level: 3 Setting: Neonatal clinic ABO incompatibility: 4/21 (19.5)
Country: Turkey
Sample Size: 21
107
Ref ID: Mean GA: Not reported. All were term babies Rh incompatibility: 4/21 (19.5%)

Mean BW: 2943 ± 533 gms G6PD deficiency: 4/21 (19.5%)
Gender M/F: 15/6
Ethnicity: Not reported Infection: Not reported
Breastfeeding: Not reported
Onset of Jaundice: Not reported Idiopathic: 10/21 (47.5%)

Exclusion: None
Author: Dawodu A Study type: Diagnosis: Jaundice Mean bilirubin levels Only subjects with indication for
Case series Criteria: TSB ≥ 205 micromol/litre TSB: 616 ± 197 micromol/litre infection were tested
Year: 1984 Setting: Hospital :
Evidence level: 3 ABO incompatibility: 15/109 (13.8%)
Country: Nigeria Sample Size: 109
Mean GA: Not reported
105
Ref ID: Mean BW: Not reported Rh incompatibility: Not reported

Gender M/F: 77/32 G6PD deficiency: 67/109 (61.5%)
Ethnicity: Not reported
Breastfeeding: Not reported
Onset of Jaundice: Not reported Infection: 24/109 (22.0%)
Idiopathic: 13/109 (11.9%)
Exclusion: None
Author: Tiker F Study type: Diagnosis: Jaundice Mean bilirubin levels Not all babies tested for G6PD levels
Case series Criteria: TSB ≥ 428 micromol/litre TSB: 515 ± 97 micromol/litre
Year: 2006 Setting: Neonatal Intensive Care Unit
Evidence level: 3
Country: Turkey Sample Size: 93 ABO incompatibility: 7/93 (7.5%)

Mean GA: 38.57 weeks Rh incompatibility: 7/93 (7.5%)
108
Ref ID: Mean BW: Not reported
Gender M/F: 51/42
Ethnicity: Not reported G6PD deficiency: 2/39 (5.1%)
Breastfeeding: 93/93 Infection: 7/93 (7.5%)
Onset of Jaundice: Day 0 - 30
Idiopathic: 61/93 (615.6%)
Exclusion: None

Kernicterus (n = 6)
ABO incompatibility: 1/6 (16.7%)

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