Page 362 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic details Study type & Patient characteristics Results Reviewers Comments
Evidence level
Rh incompatibility: 0/6 (0%)

G6PD deficiency: 1/6 (16.7%)

Infection: 3/6 (50.0%)

Idiopathic: 1/6 (16.7%)

Author: Sgro M Study type: Diagnosis: Jaundice Mean bilirubin levels
Case series Criteria: TSB ≥ 427 micromol/litre) TSB: 464 ± 75 micromol/litre
Year: 2006 Setting: Hospital
Evidence level: 3 ABO incompatibility: 49/258 (18.9%)
Country: Canada Sample Size: 258
Mean GA: 38.5 ± 1.4 weeks
111
Ref ID: Rh incompatibility: Not reported
Mean BW: 3360 ± 489 gms
Gender M/F: 162/96 Incidence of G6PD deficiency: 20/258 (7.7%)

Ethnicity: White 55.4%, Asian 24.3%, Aboriginal 7.6%, Infection: 3/258 (1.2%)
black 5.2%, Middle Eastern 4.0%, Latin American 2.8%
Breastfeeding: Not reported
Onset of Jaundice: Day 0 - 60 Idiopathic: Unclear

Exclusion: None
Author: Bjerre J Study type: Diagnosis: Jaundice Mean bilirubin levels
Case series Criteria: TSB ≥ 445 micromol/litre TSB: Not reported
Year: 2008 Setting: Hospital
Evidence level: 3 ABO incompatibility: 52/113 (46.0%)
Country: Denmark Sample Size: 113
GA (range): 35 – 42 weeks Rh incompatibility: 2/113 (0.2%)
110
Ref ID: BW (range): 2380 - 4870gms
Gender M/F: 69/44 Incidence of G6PD deficiency: 1/113 (0.9%)
Ethnicity: Not reported
Breastfeeding: Not reported Infection: Not reported
Onset of Jaundice: Day 0 - 28
Idiopathic: Unclear
Exclusion: None
Author: Necheles T Study type: Diagnosis: Severe jaundice requiring exchange transfusions Mean bilirubin levels 66 babies were in Greece and 9 were
Case series Criteria: Not reported TSB: Not reported in the USA
Year: 1976 Setting: Hospital
Evidence level: 3 ABO incompatibility: 29/75 (38.7%)
Countries: United States & Sample Size: 75
Greece GA: Not reported Rh incompatibility: 6/75 (8.0%)
BW: Not reported
109
Ref ID: Gender M/F: 69/44 Incidence of G6PD deficiency: 14/75 (18.7%)
Ethnicity: Not reported
Breastfeeding: Not reported Kernicterus
Onset of Jaundice: Not reported ABO incompatibility: 1/6 (16.7%)

254