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                                                                 Paediatric Upper Airway Obstruction  281

          has  been  used,  do  not  remove  them  but  continue  anaesthesia  via  the   The diagnosis is made by examining the throat and sending a piece
          bronchoscope and carry out a tracheostomy onto the rigid bronchoscope.  of membrane for urgent gram stain. The management is to deal with the
            Once  the  airway  is  secure,  blood  cultures  and  a  throat  swab  are   toxins and support the airway:
          carried out and IV chloamphenicol (50mg/kg body weight) is given,   •  Benzylpenicillin (50 mg/kg body weight, IV, 4-hourly). Once
          followed by 25mg/kg every 6 hours.                       drinking is established and the child is less toxic, a change is made
            The next step is to transfer the child to an ICU where the alternative   to oral penicillin. Erythromycin is an alternative.
          airway  can  be  managed.  Rapid  response  to  treatment  is  usual,  and
          extubation is possible within 24–72 hours.              •  Dexamethasone (0.6 mg/kg, twice daily, IV) if there is stridor or
                                                                   gross neck swelling.
          Retropharyngeal Abscess
            Retropharyngeal abscess is a condition most often seen in infants   •  Antitoxin is essential (60,000 units IM/IV). A test dose should be
          and young children and may mimic epiglottitis in that the symptoms   given first to ensure there is no reaction (0.1 ml of 1 in 1000 in
          of  inspiratory  stridor,  drooling,  and  a  muffled  voice  are  similar,  but   saline intradermally).
          there is always a long period of fever and general debility prior to the   •  Consider tracheostomy if airway compromised.
          diagnosis. It is due to the breakdown of a retropharyngeal adenitis into   •  Oxygen.
          an abscess and is frequently associated with tonsillitis. The child will
          usually have a stiff, painful neck, which is held to one side because the   •  Cardiac monitoring.
          midline raphe attached to the anterior cervical spine pushes the abscess   •  Bed rest for 2 weeks.
          to  one  side.  The  organisms  are  usually  Streptococcus  haemolyticus,
          Staphylococcus aureus, or anaerobes. This condition is sometimes seen   •  Nasogastric feeding if there is palatal palsy.
          in cases of tuberculosis (TB) where the cervical spine is involved and   •  Immunisation of patient and close contacts before discharge.
          caseous breakdown occurs.
            Due to the long history of preceding URTI symptoms, unlike for   Glandular Fever
          epiglottitis, it is permissible to examine the throat where an asymmetric   Glandular fever (infectious mononucleosis) is a viral infection due to
          pharyngeal  swelling  is  seen.  The  next  stage  is  a  lateral  neck  x-ray,   the  Epstein-Barr  virus,  which  may  cause  airway  obstruction  due  to
          which shows a lack of the normal lordosis and a widened space between   massive  tonsillar  enlargement.  Stertor  rather  than  stridor  is  evident,
          the spine and the pharyngeal airway. If the organism is anaerobic, a gas   examination of the neck shows large cervical glands, and the tonsils are
          bubble may be seen in the soft tissue swelling.        covered with a white membrane. The other main symptom is extreme
            The management involves urgent surgical drainage and culture of   tiredness  and  lethargy.  The  liver  and  spleen  may  be  enlarged  and  a
          the drained pus. If GA and intubation are difficult, then a No 11 blade   general lymphadenopathy may be present.
          wrapped in tape (except for its point) can be used to lance the abscess.   Treatment is mainly symptomatic with bed rest, fluids and analgesia.
          A large IV cannula could also be tried. IV antibiotics depending on the   Ampicillin should not be given since a widespread rash may occur.
          gram stain of the organism are necessary in large doses. Mediastinitis is   If the airway obstruction is present large doses of IV steroids will
          the most serious complication, with a mortality rate of 40–50%.  usually  relieve  the  obstruction  and  intubation  or  tracheostomy  is
          Diphtheria                                             rarely necessary.
          Diphtheria  is  seen  only  where  low  immunisation  levels  are  present.   Bacterial Tracheitis
          Infants are often protected by maternal antibodies, and the usual age   Bacterial tracheitis is a rare but nasty condition in which the tracheal
          group for diphtheria is 2–4 year olds.                 mucosa sloughs off to form thick crusts in the airway that are difficult
            The disease nearly always affects the pharynx, and a thick white/  to  remove.  Measles  is  not  infrequently  complicated  by  this  bacte-
          gray membrane caused by the toxin covers the tonsils and pharyngeal   rial infection, often due to Streptococcus pneumoniae or Haemophilus
          walls and bleeds if it is separated from the underlying structures. The   influenza B.
          membrane may extend to the larynx, causing stridor. Frequently, large   Children with bacterial tracheitis frequently require intubation and
          cervical lymph nodes give the appearance of a “bull neck.”   ICU  management  if  only  to  clear  the  thick  secretions.  The  child  is
            Toxaemia, which may vary from mild to severe, is the other main   much  more  toxic  with  this  bacterial  infection  than  in  viral  LTB  and
          feature  of  diphtheria  apart  from  the  respiratory  symptoms.  Severe   the absence of swallowing and drooling problems distinguish it from
          toxaemia  may  result  in  cardiovascular  collapse  and  neuropathy  and   epiglottitis.  Bronchial  complications  are  common,  and  prolonged
          include myocarditis and palatal palsy.                 treatment  with  antibiotics,  humidification,  and  physiotherapy  are
                                                                 necessary once the acute airway management has been completed.




                                                    Key Summary Points

            1.  If epiglottitis is suspected, do not examine the throat except at   6.  Immunisation against H. influenzae should be administered.
               the time of resuscitation.                        7.  In recurrent croup, suspect subglottic stenosis.
            2.  Hypoxaemia and cynanosis are very late signs.    8.  Antibiotics chloramphenicol, cefuroxime, and ampicillin should be
            3.  Dexamethasone (0.6 mgm/kg body weight orally) should be   available.
               given early. (The oral form is as effective as injected if the child   9.  Oxygen must be available.
               is able to swallow.)
                                                                 10. If intubation is considered, make sure personnel are available to
            4.  Nebulised epinephrine (1 ml in 1/1000 in 3 ml of 0.9% saline)   carry out tracheostomy in case intubation fails.
               should be available.
            5.  History taking and resuscitation should take place at the same time.
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