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286  Tracheomalacia
        Table 43.5: Evidence-based research.
           Title     Aortopexy for tracheomalacia in oesophageal anomalies
           Authors   Corbally MT, Spitz L, Kiely E, Brereton RJ, Drake DP
           Institution  The Hospital for Sick Children, Great Ormond Street,
                     London, UK
           Reference  Eur J Pediatr Surg 1993; 5:264–266
           Problem   The problem is significant symptomatic tracheomalacia in
                     association with repaired congenital oesophageal anomalies.
                     Indications for surgery included recurrent apnoea/cyanosis
                     (31), “near fatal episodes” (16), recurrent respiratory distress
                     and infections (20), and worsening stridor (15).
           Intervention  Aortopexy
           Comparison/
           control   Case review (level 4). A review of 48 patients over a ten-
           (quality of   year period who underwent an aortopexy for tracheomalacia
                     following repair of an oesophageal anomaly.
           evidence)
           Outcome/  Gastro-oesophageal reflux was also noted in 30 cases.
           effect    Aortopexy cured near fatal episodes in all patients and
                     resulted in improvement of airway obstruction in 95%. Failure
                     in two patients was due to unrecognised bronchomalacia.
           Historical
           significance/  Aortopexy was recommended as the primary procedure of
                     choice for significant tracheomalacia.
           comments

                                                  Key Summary Points

           1.  An association exists between oesophageal atresia and/or   4.  An aortopexy gives excellent results for localised
              tracheo-oesophageal fistula (OA/TOF) and tracheomalacia.  tracheomalacia in association with OA and TOF.
           2.  Expiratory stridor should be investigated by bronchoscopy        5.  Severe gastro-oesophageal reflux may be associated with
              in a self-ventilating patient.                      tracheomalacia and may require a fundoplication.
           3.  Anterior-posterior collapse of the tracheal lumen indicates   6.  Vascular anomalies associated with tracheomalacia require
              severe tracheomalacia, and urgent intervention should be   specialised investigations and management in a paediatric
              considered.                                         cardiothoracic unit.




                                                       References

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