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286 Tracheomalacia
Table 43.5: Evidence-based research.
Title Aortopexy for tracheomalacia in oesophageal anomalies
Authors Corbally MT, Spitz L, Kiely E, Brereton RJ, Drake DP
Institution The Hospital for Sick Children, Great Ormond Street,
London, UK
Reference Eur J Pediatr Surg 1993; 5:264–266
Problem The problem is significant symptomatic tracheomalacia in
association with repaired congenital oesophageal anomalies.
Indications for surgery included recurrent apnoea/cyanosis
(31), “near fatal episodes” (16), recurrent respiratory distress
and infections (20), and worsening stridor (15).
Intervention Aortopexy
Comparison/
control Case review (level 4). A review of 48 patients over a ten-
(quality of year period who underwent an aortopexy for tracheomalacia
following repair of an oesophageal anomaly.
evidence)
Outcome/ Gastro-oesophageal reflux was also noted in 30 cases.
effect Aortopexy cured near fatal episodes in all patients and
resulted in improvement of airway obstruction in 95%. Failure
in two patients was due to unrecognised bronchomalacia.
Historical
significance/ Aortopexy was recommended as the primary procedure of
choice for significant tracheomalacia.
comments
Key Summary Points
1. An association exists between oesophageal atresia and/or 4. An aortopexy gives excellent results for localised
tracheo-oesophageal fistula (OA/TOF) and tracheomalacia. tracheomalacia in association with OA and TOF.
2. Expiratory stridor should be investigated by bronchoscopy 5. Severe gastro-oesophageal reflux may be associated with
in a self-ventilating patient. tracheomalacia and may require a fundoplication.
3. Anterior-posterior collapse of the tracheal lumen indicates 6. Vascular anomalies associated with tracheomalacia require
severe tracheomalacia, and urgent intervention should be specialised investigations and management in a paediatric
considered. cardiothoracic unit.
References
1. Stringer MD, Oldham KT, Mouriquand DE. Pediatric Surgery and 9. Morabito A, MacKinnon E, Alizai N, Asero L, Bianchi A. The
Urology: Long-Term Outcomes, 2nd ed. Cambridge University anterior mediastinal approach for management of tracheomalacia.
Press, 2006. J Pediatr Surg 2000; 35(10):1456–1458.
2. Filler RM, et al. Life-threatening anoxic spells caused by tracheal 10. van der Zee DC, Bax KN. Thorascopic treatment of esophageal
compression. J Pediatr Surg 1976; 11:739–748. atresia with distal fistula and of tracheomalacia. Semin Pediatr
3. Benjamin B, et al. Tracheomalacia in association with T.O.F. Surg 2007; 16(4):224–230.
Surgery 1976; 79:504–508. 11. Kane TD, Nadler EP, Potoka DA. Thorascopic aortopexy for
vascular compression of the trachea: approach from the right. J
4. Wailoo MP, Emery JL. The trachea in children with T.O.F. Laparoendoscopic Adv Surg Tech A. 2008; 18(2):313–316.
Histopathology 1979; 3:329–338.
5. Pole RJ, Qi BQ, Beasley SW. Abnormalities of the tracheal 12. Anton-Pacheco J.L. Cabezali D, Tejedor R, et al. The role of
cartilages in the rat fetus with tracheo-oesophageal fistula or airway stenting in pediatric tracheobronchial obstruction. Eur J
tracheal agenesis. Pediatr Surg Int 2001; 17:25–28. Cardiothorac Surg 2008; 33(6):1069–1075. Epub 2008 Mar 4.
13. Cozzi F, Morini F, Casati A, et al. Glossopexy as an alternative to
6. Kiely EM, Spitz L, Brereton R. Management of tracheomalacia by aortopexy in infants with repaired esophageal atresia and upper
aortopexy. Pediatr Surg Int 1987; 2:13–15. airway obstruction. J Pediatr Surg 2002; 37(2):202–206.
7. Kimura K, et al. Aortosternopexy for tracheomalacia, technical
refinement. J Pediatr Surg 1990; 25:769–772. 14. Filler RM, Messineo A, Vinograd I. Severe tracheomalacia
associated with esophageal atresia: results of surgical treatment.
8. Corbally MT, Spitz L, Kiely E, Brereton RJ, Drake DP. Aortopexy J Pediatr Surg 1992; 27(8):1136–1140; discussion 1140–1141.
for tracheomalacia in oesophageal anomalies. Eur J Pediatr Surg
1993; 3:264–266.