Page 34 - LECTURE NOTES
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The etiologic agents are various strains of  Human papilloma virus (HPV).  The

               incubation period of a wart is 2 to 9  months during which time an excessive
               proliferation of skin growth slowly develops. They can be spread by direct or indirect

               contact or autoinoculation.  The hosts’ immunity clears the warts within two years in
               2/3 of the cases so treatment is often unnecessary


               Most types of HPV have an affinity for the skin and produce common warts (verruca

               vulgaris), flat warts (verruca plana), and plantar or foot warts (verruca plantaris).

               Several other types of HPV have an affinity for mucous membranes and some of these
               cause ano-genital warts (condyloma acuminata) which is mostly sexually transmitted

               infection. Certain strains of HPV increase the risk of cervical cancer.

               In immunodeficiency states warts can become fulminantly wide spread and difficult to
               treat.


               There is no single effective treatment for warts. Management is based on the age of

               the individual as well as the size, number, and location of warts.  Common warts,

               especially in children, do not necessarily need to be treated, because they exhibit a
               high rate of spontaneous remission.  Without treatment, however, spread can occur.


                Treatment



               ™ Salicylic acid 25% ointment twice daily followed by cutting or scraping

               ™ Preparation of salicylic acid 5-20% and lactic acid 5-20  in collodion are easier to use
               ™ Electrodessication and curettage

               ™ Freezing with liquid nitrogen if available.



                 For genital warts

               ™ Podophyllin 10-25% solution.  Protect the skin around the wart with Vaseline apply
                   the podophyllin with a match stick carefully on the top of the war and wash after 6

                   hours. Repeat every week. It is contraindicated in pregnancy.

               ™ Phenol 80% can be used in the same fashion to Podophyllin.
               ™ Cauterization



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