Page 66 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

Modi 2006 (Continued)

Acceptable reference standard? Yes Yes, coronary angiography with a reference
All tests standard threshold of ≥ 50% stenosis

Acceptable delay between tests? Unclear Unclear, but likely to be only short delay
All tests between tests.

Partial verification avoided? Yes All participants who received an index test
All tests received the reference standard test
Differential verification avoided? Yes This was not an issue in this study. Disease
All tests status (CAD) is diagnosed only through
coronary angiography

Incorporation avoided? Yes This was not an issue in this study. Disease
All tests status (CAD) is diagnosed only through
coronary angiography

Reference standard results blinded? Yes Reference standard performed before index
All tests test. Therefore it was not influenced by re-
sults of index test

Index test results blinded? Yes An operator, who was blinded with respect
All tests to the results of the coronary angiography,
measured CIMT in all patients prior to
coronary angiography and recorded it on
videotape. Two independent observers who
were blinded to the result of coronary an-
giography, measured CIMT offline to vali-
date its predictive accuracy as a noninvasive
test in predicting the presence or absence
of CAD

Relevant clinical information? Yes Relevant clinical information was provided
All tests regarding the performance and analysis of
both the index and reference tests

Uninterpretable results reported? Yes No results were reported to be uninter-
All tests pretable.

Withdrawals explained? Yes No withdrawals were present.
All tests

Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review) 64
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.