Page 65 - Cardiac testing for coronary artery disease in potential kidney transplant recipients
P. 65

Marwick 1990  (Continued)



                 Uninterpretable results reported?  Yes                        No results were reported to be uninter-
                 All tests                                                     pretable.

                 Withdrawals explained?         Yes                            No withdrawals were reported.
                 All tests

                Modi 2006

                 Clinical features and settings  Clinical features
                                                  • ESKD patients with hypertension on maintenance dialysis undergoing pre-
                                                transplant coronary angiography as per the institutional protocol if they were aged > 40
                                                years to rule out CAD as part of transplant workup
                                                Setting
                                                  • Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

                 Participants                     • Number: 105
                                                  • DM: 61/105 (58%)
                                                  • Hypertension: all were hypertensive
                                                  • Sex: 102 (97.1%) male
                                                  • Age (mean ± SD): 51.6 ± 6.2 years (range 38 to 64 years)

                 Study design                   Cross sectional study.

                 Target condition and reference standard(s) Coronary artery stenosis measured by coronary angiography
                                                  • CAD defined as presence of ≥ 1 coronary arteries with ≥ 50% diameter stenosis
                 Index and comparator tests     CIMT measurement
                                                  • CIMT measurement was conducted on USG B mode 7.5 MHZ probe. At least
                                                three readings were taken, and the average of three readings was taken for evaluation.
                                                IMT on both sides was calculated and averaged. Plaques were defined as focal widening
                                                relative to the adjacent segments, with protrusion into the lumen, composed either of
                                                only calcified deposits or a combination of calcification and non-calcified material. The
                                                site and extent of lesions were not quantified.
                                                  • Patients were further divided into two groups according to average CIMT
                                                (average IMT > 0.75 mm and those with IMT < 0.75 mm).

                 Follow-up                      None reported.

                 Notes

                 Table of Methodological Quality

                 Item                           Authors’ judgement             Description

                 Representative spectrum?       Yes                            ESKD patients undergoing cardiac evalua-
                 All tests                                                     tion as part of transplant workup




                Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review)  63
                Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
   60   61   62   63   64   65   66   67   68   69   70