Page 508 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C4.2. Comparison between watchful waiting and radical prostatectomy (continued)
                                        Author, Year         Study name       Comparison           Outcome            Followup      Sample size      Results                          Factors included in the
                                        [Pubmed ID]          /Database                             definition/        (yr)          per group                                         model
                                                                                                   measurement
                                        Study design                                               instrument
                                                                              Observation vs.      HRQoL              2 yr post-    Observation:     Estimates are means (SE)         Treatment group
                                                                              RP                   questionnaire      treatment     87               based on linear mixed            interaction with time,
                                                                                                   composed of        regression    RP: 351          model for Observation vs.        age, time of treatment.
                                                                                                   items from the     estimates                      RP:
                                                                                                   RAND-36 item                                      Physical functioning, 70.8       P values for
                                                                                                   Health Survey.                                    (5.5); 85.8 (2.3)                comparisons between
                                                                                                   All scales were                                   Role-physical, 62.8 (9.1);       treatment groups NR.
                                                                                                   scored 0 to                                       72.3 (4.0)
                                                                                                   100; optimal                                      Role-emotional, 72.5 (8.0);
                                                                                                   health or                                         84.4 (3.4)
                                                                                                   functioning =                                     Emotional well-being, 75.9
                                                                                                   100.                                              (3.4); 86.0 (1.5)
                                                                                                                                                     Bodily pain, 76.1 (4.9); 84.4
                                                                                                                                                     (2.2)
                                                                                                                                                     Social functioning, 77.9
                                                                                                                                                     (5.1); 88.8 (2.3)
                                                                                                                                                     Energy/fatigue, 57.1 (4.4);
                                                                                                                                                     70.9 (2.0)
                                                                                                                                                     General health perception,
                                                                                                                                                     53.8 (4.8); 74.6 (2.1)
                                                                                                                                                     Health change, 46.4 (5.5);
                                                                                                                                                     60.2 (2.4)
                                                                                                                                                     Health distress, 85.0 (4.2);
                                                                                                                                                     91.3 (1.9)
                                                                                                                                                     Self-esteem, 88.2 (4.0); 87.7
                                                                                                                                                     (1.7)

























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