Page 511 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.2. Comparison between watchful waiting and radical prostatectomy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
Observation vs. Prostate Immediate Observation: Estimates are means (SE) Treatment group
RP cancer-specific post- 87 based on linear mixed interaction with time,
QoL items. All treatment RP: 351 model for Observation vs. age, time of treatment.
scales were period RP:
scored 0 to regression Urinary function, 81.9 (2.5); P values for
100; optimal estimates 43.4 (1.3) comparisons between
health or Bowel function, 82.5 (1.9); treatment groups NR.
functioning = 78.1 (1.0)
100. Sexual function, 37.0 (2.4);
10.3 (1.3)
Urinary bother, 66.4 (3.3);
48.0 (1.7)
Bowel bother, 81.8 (2.8);
64.7 (3.1)
Sexual bother, 45.2 (4.3);
33.3 (2.3)
CaP interference: family
function, 81.1 (2.3); 81.9
(1.2)
CaP interference, 83.0 (2.0);
65.8 (1.0)

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