Page 514 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C4.2. Comparison between watchful waiting and radical prostatectomy (continued)
                                        Author, Year         Study name       Comparison           Outcome            Followup      Sample size      Results                          Factors included in the
                                        [Pubmed ID]          /Database                             definition/        (yr)          per group                                         model
                                                                                                   measurement
                                        Study design                                               instrument
                                                                              Observation vs.      Prostate           2 yr post-    Observation:     Estimates are means (SE)         Treatment group
                                                                              RP                   cancer-specific    treatment     87               based on linear mixed            interaction with time,
                                                                                                   QoL items. All     regression    RP: 351          model for Observation vs.        age, time of treatment.
                                                                                                   scales were        estimates                      RP:
                                                                                                   scored 0 to                                       Urinary function, 87.4 (5.1);    P values for
                                                                                                   100; optimal                                      70.7 (2.3)                       comparisons between
                                                                                                   health or                                         Bowel function, 89.1 (3.9);      treatment groups NR.
                                                                                                   functioning =                                     88.1 (1.7)
                                                                                                   100.                                              Sexual function, 29.1 (4.9);
                                                                                                                                                     26.8 (2.2)
                                                                                                                                                     Urinary bother, 83.6 (6.7);
                                                                                                                                                     80.7 (3.0)
                                                                                                                                                     Bowel bother, 90.0 (5.6);
                                                                                                                                                     90.2 (2.5)
                                                                                                                                                     Sexual bother, 24.9 (8.8);
                                                                                                                                                     46.7 (3.9)
                                                                                                                                                     CaP interference: family
                                                                                                                                                     function, 86.9 (4.6); 88.6
                                                                                                                                                     (2.1)
                                                                                                                                                     CaP interference, 87.0 (4.1);
                                                                                                                                                     90.6 (1.8)

































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