Page 328 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 328

Appendix Table C1.14. Treatment characteristics—changes in treatment patterns over time (continued)
                                        Author                Database         Treatment          1980-     1985-89        1990-94        1995-     2000-04      2005-     Statistical          Notes
                                        Year                                                      84                                      99                     10        analysis
                                        PMID
                                                                               RP                                                                                          RP: + 63.5%          Black men
                                                                               RT                                                                                          RT: +73.5%           only
                                                                               Conservative                 (1986)         (1993)                                          Conservative Tx:
                                                                               Tx (not                                                                                     -37.4%
                                                                               radiotherapy or
                                                                               surgery)                                                                                    (change in the
                                                                                                                                                                           proportion of men
                                                                                                                                                                           receiving each Tx
                                                                                                                                                                           over the study
                                                                                                                                                                           period, 1986-93).
                                                                               Baseline yr =                1.12 (1.00     1.39 (1.27                                      Logistic
                                                                               1986                         to 1.24)       to 1.53)                                        regression
                                                                               OR (95% CI)                                                                                 predicting Tx
                                                                               receiving                                                                                   received based
                                                                               aggressive Tx                (1987)         (1992)                                          on diagnosis yr;
                                                                               versus non                                                                                  adjusted for age,
                                                                               aggressive Tx                                                                               socioeconomic
                                                                                                                                                                           status, SEER
                                                                                                                                                                           registry, tumor
                                                                                                                                                                           grade,
                                                                                                                                                                           comorbidity
                                                                                                                                                                           score, and the
                                                                                                                                                                           race x TURP
                                                                                                                                                                           interaction





























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