Page 330 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C1.14. Treatment characteristics—changes in treatment patterns over time (continued)
Author Database Treatment 1980- 1985-89 1990-94 1995- 2000-04 2005- Statistical Notes
Year 84 99 10 analysis
PMID
87
Warren SEER- Cancer-related 54% 24% -2.52 (-2.97, - All cancer
2008 Medicare surgery 33% 47% 2.07), P<0.001 stages; some
18544740 RT 4% 7% 1.40 (0.95, 1.84), patients had
Chemotherapy 35% 24% P<0.001 claims for
Hospitalizations (1991) (2002) 0.15 (-0.03, 0.35), more than one
for reasons P=0.09 services.
other than -0.79 (-1.03, -
cancer surgery 0.56), P<0.001
[proportions
calculated [annual % rate of
among patients decline (slopes
with claims for from linear
specific cancer regression of the
services] proportion of men
receiving each
treatment over
time]
No initial 21% 30% NR All cancer
cancer-related (1991) (2002) stages
surgery,
radiation
therapy, or
chemotherapy
(“expectant
management”)
88
Gross SEER- “Definitive 81.7% 77.9% NR Proportions
2008 Medicare therapy” (BT or adjusted for
18181101 EBRT or RP) 18.3% 22.1% age, marital
No “definitive (1992-94) (2000- status,
therapy” 02) physician
[White] visits,
geographic
region, cancer
stage and
grade and
comorbid
conditions

C-83