Page 327 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 327

Appendix Table C1.14. Treatment characteristics—changes in treatment patterns over time (continued)
 Author   Database   Treatment   1980-  1985-89   1990-94   1995-  2000-04   2005-  Statistical   Notes
 Year   84      99                     10       analysis
 PMID
                                                p<0.001 for
                                                definitive therapy
                                                in each yr
                                                compared to
                                                White men). This
                                                disparity was less
                                                profound than it
                                                had been in 1992
                                                (OR 0.56 and
                                                0.38,
                                                respectively).
 47
 Underwood    SEER   ADT/EM         (1992)   (1999)        Logistic   “the utilization
 2005                                           regression for       of ADT/EM
 15612083                                       trends in Tx         decreased
                                                P<0.001              significantly
                                                                     over time.”
                                                                     Additional
                                                                     information
                                                                     (1992-99) was
                                                                     presented in a
                                                                     figure in the
                                                                     article. Data
                                                                     were not
                                                                     available for
                                                                     assessing
                                                                     ADT and EM
                                                                     separately.
 58
 Klabunde    SEER,   RP                         RP: + 58.5%          White men
 1998    Medicare   RT                          RT: +39.2%           only
 9749657   Conservative   (1986)   (1993)       Conservative Tx:
 Tx (not                                        -38.4%
 radiotherapy or
 surgery)                                       (change in the
                                                proportion of men
                                                receiving each Tx
                                                over the study
                                                period, 1986-93).








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