Page 293 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C1.7. Tumor characteristics—stage (continued)
 Author   Database   Stage groups   1980-84   1985-  1990-94   1995-99   2000-04   2005-  Statistical   Notes
 Year   89                             10        analysis
 PMID
 75
 Mettlin    NCDB   Stage
 1998   0   5.4%   2.0%                          NR
 9781963   I   22.8%   24.9%
 II   41.1%   49.7%
 III   18.0%   13.0%
 IV   12.6%   10.3%
 Localized disease   69.3%   76.7%
 (0-II)   (1992)   (1995)
 91
 Mettlin    NCDB   AJCC stage                     NR
 1999   0   4.5%   2%
 10547563   I    19%   23.5%
 II   34%    46%
 III   15%   12%
 IV   10%    8%
 Unknown   18%   8%
 (1992)      (1996)
 76
 Danley    LAC/USC   Localized   71%   66%               1.03 (0.96,
 1995    CSP   Regional/Metastatic  29%   34%    1.10)
 8580296   Percentage of   (1981-  (1985-        1.29 (1.21,
 cases by yr of   84)   88)                      1.37)
 diagnosis                                       (OR and 95%
                                                 CIs using
                                                 1976-80 as the
                                                 baseline
                                                 period)

                                                 P<0.001 for
                                                 trend over time
 Ordering of the studies follows Appendix Table C1.1.
 AJCC = American Joint Committee on Cancer; cAJC = clinical stage according to American Joint Committee on Cancer guidelines; CI = confidence interval; NA = not applicable;
 NR = not reported; OR = odds ratio; pAJCC = pathological stage according to American Joint Committee on Cancer guidelines; PMID = PubMed identification number; PSA =
 prostate-specific antigen; SD = standard deviation.

















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