Page 292 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C1.7. Tumor characteristics—stage (continued)
                                        Author               Database      Stage groups            1980-84     1985-      1990-94       1995-99      2000-04     2005-     Statistical       Notes
                                        Year                                                                   89                                                10        analysis
                                        PMID
                                              75
                                        Mettlin              NCDB          Stage
                                        1998                               0                                              5.4%          2.0%                               NR
                                        9781963                            I                                              22.8%         24.9%
                                                                           II                                             41.1%         49.7%
                                                                           III                                            18.0%         13.0%
                                                                           IV                                             12.6%         10.3%
                                                                           Localized disease                              69.3%         76.7%
                                                                           (0-II)                                         (1992)        (1995)
                                              91
                                        Mettlin              NCDB          AJCC stage                                                                                      NR
                                        1999                               0                                              4.5%          2%
                                        10547563                           I                                              19%           23.5%
                                                                           II                                             34%           46%
                                                                           III                                            15%           12%
                                                                           IV                                             10%           8%
                                                                           Unknown                                        18%           8%
                                                                                                                          (1992)        (1996)
                                               76
                                        Danley               LAC/USC       Localized               71%         66%                                                         1.03 (0.96,
                                        1995                 CSP           Regional/Metastatic  29%            34%                                                         1.10)
                                        8580296                            Percentage of           (1981-      (1985-                                                      1.29 (1.21,
                                                                           cases by yr of          84)         88)                                                         1.37)
                                                                           diagnosis                                                                                       (OR and 95%
                                                                                                                                                                           CIs using
                                                                                                                                                                           1976-80 as the
                                                                                                                                                                           baseline
                                                                                                                                                                           period)

                                                                                                                                                                           P<0.001 for
                                                                                                                                                                           trend over time
                                        Ordering of the studies follows Appendix Table C1.1.
                                        AJCC = American Joint Committee on Cancer; cAJC = clinical stage according to American Joint Committee on Cancer guidelines; CI = confidence interval; NA = not applicable;
                                        NR = not reported; OR = odds ratio; pAJCC = pathological stage according to American Joint Committee on Cancer guidelines; PMID = PubMed identification number; PSA =
                                        prostate-specific antigen; SD = standard deviation.

















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