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Diarrhoea and vomiting caused by gastroenteritis in children under 5 years




                        ORT costing

                        The  patient  population  is  defined  by  attendance  at  the  emergency  department.  There  are
                        opportunity  costs  associated  with  an  emergency  department  attendance  (administration,
                        cleaning, bed changing, etc.) over and above those relating directly to treatment. However, these
                        opportunity costs do not vary by treatment method and therefore capital costs associated with the
                        use of emergency department facilities can be excluded from the analysis.
                        ORT costs therefore include only staff and consumable costs. This is due to the omission of
                        emergency department related costs and because patients are discharged following treatment in
                        the emergency department.
                        Patients undergo a clinical examination prior to receiving ORT; this is done by a specialty registrar.
                        Patients are then reviewed hourly for the 4 hours they spend in the emergency department; this
                        takes approximately 5 minutes per hour (total of 20 minutes) and is done by a nurse (band 5).
                        Patients also receive education/information regarding the treatment they are being given, also
                        done by a nurse (band 5). This takes approximately 10 minutes.
                        Table A.3 shows the time taken to carry out ORT-related tasks and the associated costs. Column 2
                        displays the times used in the base case analysis. The range of times and costs used for both base
                        case and ‘worst case’ analyses is given in brackets.
                        Each patient receives an average of two sachets of Dioralyte for ORT, which is given using a
                        200 ml bottle. Table A.4 summarises the costs for these consumables.
                        No equipment is required for ORT treatment. It is assumed that all children are discharged from
                        the emergency department once they have received ORT.

                        IVT costing
                        As above for the ORT costing, emergency department attendance costs are omitted from the costing
                        of IVT. All children on IVT are given approximately 500 ml of sodium chloride 0.9% saline. *

                        Table A.5 shows the range of time taken to carry out IVT-related tasks and associated costs. Baseline
                        observations, equipment adjustments and site checks are carried out hourly for the first 4 hours,
                        i.e. during their time in the emergency department. These are all carried out by a band 5 nurse.
                        Table A.6 summarises the cost of consumables used in carrying out IVT.
                        The model assumes that all children on IVT are admitted for an inpatient stay, where they complete
                        IV treatment. This inpatient stay includes any costs of further treatment during the patient’s stay in
                        hospital We use the costs of ‘Infectious and non-infectious gastroenteritis without complications
                        (non-elective)’ as the NHS Healthcare Resource Group (HRG) code for this admission (Table A.7).
                        The range of costs used for both base case and ‘worst case’ analysis is given in brackets.
                        Drip stands and infusion pumps are equipment pieces included in the costing of IVT and both of
                        these are used for the 24 hour period of IVT. Costs for these are shown in Table A.8.
                        A number of blood tests are carried out when patients are treated with IVT and these are costed
                        using a ‘Pathology indicative tariff for haematology’ from the NHS National Tariff and are shown
                        in Table A.9.

                        Further IVT costing
                        The model assumes that if a child remains dehydrated after the initial 24 hours of IVT, treatment
                        continues for another period of 24 hours. Patients receiving further treatment require additional
                        resources. Further IVT requires a longer inpatient stay and the model assumes that the costs of this
                        additional stay are given by the difference between the cost of a hospital episode for infectious
                        and non-infectious gastroenteritis with complications and the cost without complications. This
                        additional hospital stay is inclusive of any additional labour, consumables or equipment costs.
                        Table A.10 summarises the hospital costs used in the analysis, and the range of costs used for
                        both base case and ‘worst case’ analysis are given in brackets.

                        *  In practice, most children are given less than 500 ml of saline. The smallest bag of saline available, however, is of 500 ml and once
                         opened cannot be reused. The cost used in the analysis therefore is that of a 500 ml bag.


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