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Appendix A




                           Figure A.2 shows the one-way sensitivity analysis for the probability of phlebitis. This probability
                           is ranged from 1 to 10% to illustrate how this changes the incremental costs of IVT. Figure A.3
                           shows the one-way sensitivity analysis for the probability of paralytic ileus, again ranging from
                           1 to 10%. Finally, Figure A.4 shows the one-way sensitivity analysis with varying costs of ORT
                           (this can be considered equivalent to a sensitivity analysis varying the cost differential between
                           ORT and IVT).
                           Multi-way sensitivity analysis is where several parameters values are changed simultaneously,
                           although one of the difficulties with this technique is the huge number of possible permutations
                           that may exist. An alternative method to evaluate the uncertainty across several model parameters
                           is  to  use  a  technique  called  probabilistic  sensitivity  analysis  (PSA).  This  involves  setting  a



































                           Figure A.2  One-way sensitivity analysis varying the probability of phlebitis as a complication of IVT

































                          Figure A.3  One-way sensitivity analysis varying the probability of paralytic ileus


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