Page 6 - Pagetit

CONTENTS

Tolerance and withdrawal 74
Neurobiological adaptations to prolonged use 75
Tobacco 75
Introduction 75
Behavioural effects 75
Mechanism of action 76
Tolerance and withdrawal 77
Pharmacological treatment of nicotine dependence 78
Opioids 79
Introduction 79
Behavioural effects 79
Mechanism of action 80
Tolerance and withdrawal 80
Neurobiological adaptations to prolonged use 81
Pharmacological treatment of opioid dependence 81
Cannabinoids 84
Introduction 84
Behavioural effects 85
Mechanism of action 86
Tolerance and withdrawal 87
Neurobiological adaptations to prolonged use 88
Cocaine (hydrochloride and crack) 89
Introduction 89
Behavioural effects 89
Mechanism of action 89
Tolerance and withdrawal 91
Neurobiological adaptations to prolonged use 91
Pharmacological treatment of cocaine dependence 92
Amphetamines 93
Introduction 93
Behavioural effects 94
Mechanism of action 95
Tolerance and withdrawal 95
Neurobiological adaptations to prolonged use 96
Ecstasy 96
Introduction 96
Behavioural effects 99
Mechanism of action 99
Tolerance and withdrawal 100
Neurobiological adaptations to prolonged use 100
Volatile solvents 100
Introduction 100
Behavioural effects 101
Mechanism of action 102

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Pagetit 5 19.1.2004, 12:36