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Neuroscience of psychoactive
substance use and dependence
The Neuroscience of psychoactive substance use and dependence
provides an authoritative summary of current knowledge of the
biological basis of substance use and dependence, and discus-
ses the relationship of these behaviours with environmental fac-
tors. The book focuses on specific brain mechanisms governing
craving, tolerance, withdrawal, and dependence on a wide range
of psychoactive substances, including tobacco, alcohol and illicit
drugs. The ethical implications of new developments for preven-
tion and treatment are also discussed, and the public health
implications of this knowledge are translated into recommenda-
tions for policy and programmes at national and international
levels. Relying on contributions from many international experts, Neuroscience of psychoactive substance use and dependence
the best available evidence is presented from the various schools
of thought and areas of research in this rapidly growing field.
Neuroscience of psychoactive substance use and dependence is
written for individuals with more than a basic knowledge of the
field, including scientists from a variety of disciplines. The book
should be of interest to health care workers, clinicians, social
workers, university students, science teachers and policy makers.
ISBN 92 4 156235 8
WHO