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      brain opiate receptors and allows normalization of brain function, so
      the patient starts ‘acting normal.’

      Reduction In Medical Problems By Methadone Maintenance
      Treatment

      Some of the benefits of methadone maintenance treatment are related
      to reduction in illness, whether related to opiates or to other dangerous
      practices that are tied to active addiction.

      For example, stopping injection drug use reduces admissions to
      hospitals for abscesses or other skin infections, or endocarditis (heart
      infection). It has been very clearly documented that methadone
      maintenance treatment reduces the sero-conversion to HIV.
      In the case of pregnant women on MMT, babies will be born healthier
      by avoiding heroin.

      As shown above in the outcomes table, MMT saves lives (reduces the
      death rate, or mortality). Most of  these addiction-related deaths are
      opiate overdoses, when actively addicted persons inject too much
      heroin at one time and stop breathing.

      Table 3

      Medical problems related to opiate addiction
      Opiate overdose and death
      HIV infection from contaminated needles. Patients may develop
      AIDS.
      Hepatitis B or C from contaminated needles, cookers, cotton, water.
      Chronic hepatitis may lead to cirrhosis and liver failure.
      Endocarditis (heart infection) from contaminated injection into the
      bloodstream. Heart valves are destroyed and may require open heart
      surgery.
      Abscess or cellulitis from contaminated needle injection into the
      skin and subcutaneous tissue. May require incision and drainage, or
      IV antibiotics.
      Necrotizing fasciitis from contaminated needles. Large areas of skin
      and muscle tissue may be lost, even if the patient survives.
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