Page 81 - AIDSBK23C

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Category N: Not symptomatic. Children who have no signs or symptoms considered to
be the result of HIV infection or who have only one of the conditions listed in Category
A.

Category A: Mildly symptomatic. Children with two or more of the conditions listed
below but none of the conditions listed in Category B and C.

* Lymphadenopathy (≥0.5 cm at more than two sites; bilateral = one site)
* Hepatomegaly
* Splenomegaly
* Dermatitis
* Parotitis
* Recurrent or persistent upper respiratory infection, sinusitis, or otitis media

Category B: Moderately symptomatic. Children who have symptomatic conditions
other than those listed for Category A or C that are attributed to HIV infection.

Examples of conditions in clinical Category B include but are not limited to:

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* Anemia (<8 gm/dL), neutropenia (<1000/mm ), or thrombocytopenia
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(<100,000/mm ) persisting ≥30 days
* Bacterial meningitis, pneumonia, or sepsis (single episode)
* Candidiasis, oropharyngeal (thrush), persisting (>2 months) in children > 6 months of age
* Cardiomyopathy
* Cytomegalovirus infection, with onset before one month of age
* Diarrhea, recurrent or chronic
* Hepatitis
* Herpes simplex virus (HSV) stomatitis, recurrent (more than 2 episodes within 1 year)
* Varicella (herpes) zoster virus (shingles) involving at least two distinct episodes of more
than one dermatome
* Leiomyosarcoma
* Lymphoid interstitial pneumonitis (LIP) or pulmonary lymphoid hyperplasia complex
* Nephropathy
* Nocardiosis
* Persistent fever (lasting 1 month)
* Toxoplasmosis with onset before 1 month of age
* Varicella, disseminated (complicated chicken pox)

Category C: Severely symptomatic. Children who have any condition listed in the 1987
surveillance case definition for acquired immunodeficiency syndrome with the exception
of LIP. Conditions included in clinical Category C for children infected with human
immunodeficiency virus (HIV) include:

* Serious bacterial infections, multiple or recurrent (i.e., any combination of at least two
culture-confirmed infections within a 2-year period), of the following types: septicemia,
pneumonia, meningitis, bone or joint infection, or abscess of an internal organ or body