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cavity (excluding otitis media, superficial skin or mucosal abscesses, and indwelling
catheter-related infections)
* Candidiasis, esophageal or pulmonary (bronchi, trachea, lungs)
* Coccidioidomycosis, disseminated (at a site other than or in addition to lungs or cervical
or hilar lymph nodes)
* Cryptococcosis, extrapulmonary
* Cryptosporidiosis or isosporiasis with diarrhea persisting >1 month
* Cytomegalovirus disease with onset of symptoms at age >1 month (at a site other than
liver, spleen, or lymph nodes)
* Encephalopathy (for criteria, see section in Central Nervous System Pathology in AIDS)
* Herpes simplex virus infection causing a mucocutaneous ulcer that persists for >1 month;
or bronchitis, pneumonitis, or esophagitis for any duration affecting a child >1 month of
age
* Histoplasmosis, disseminated (at a site other than or in addition to lungs or cervical or
hilar lymph nodes)
* Kaposi's sarcoma
* Lymphoma, primary, in brain
* Lymphoma, small, noncleaved (Burkitt), or immunoblastic or large cell lymphoma of
B-cell or unknown immunologic phenotype
* Mycobacterium tuberculosis, disseminated or extrapulmonary
* Mycobacterium, other species or unidentified species, disseminated (at a site other than or
in addition to lungs, skin, or cervical or hilar lymph nodes)
* Mycobacterium avium complex or Mycobacterium kansasii, disseminated (at a site other
than or in addition to lungs, skin, or cervical or hilar lymph nodes)
* Pneumocystis jiroveci (carinii) pneumonia
* Progressive multifocal leukoencephalopathy
* Salmonella (non typhoid) septicemia, recurrent
* Toxoplasmosis of the brain with onset at >1 month of age
* Wasting syndrome in the absence of concurrent illness other than HIV infection that
could explain the following findings:
a) persistent weight loss >10% of baseline
or:
b) downward crossing of at least two of the following percentile lines on the weight-
for-age chart (e.g., 95th, 75th, 50th, 25th, 5th) in a child ≥1 year of age
or:
c) <5th percentile on weight-for-height chart on two consecutive measurements, ≥30
days apart PLUS a) chronic diarrhea (i.e., at least two loose stools per day for ≥30
days) OR b) documented fever (for ≥30 days, intermittent or constant)