Page 65 - LECTURE NOTES

Disseminated furunculosis, gingivitis, gangrenous stomatitis, and abscess formation

can occur in patients with HIV infection.

Fungal infections
Superficial fungal infections

Recurrent and persistent mucocutaneous candidiasis is common in patients with HIV

infection. In the United States, recurrent vaginal candidiasis is the most common
presentation of HIV infection in women.

In adults, generalized dermatophytosis, or Tinea capitis, which is typically caused by
Trichophyton rubrum, may suggest HIV infection.

Pityriasis versicolor may be persistent, generalized and recurrent in patients with HIV
infection.

Deep fungal infections

Cutaneous Cryptococcus may be observed in patients with HIV infection, but it is rare.
Clinical manifestations include cellulitis; papules; plaques; ulcers; or translucent dome-

shaped papules with central umbilication, resembling MC.

Cutaneous histoplasmosis may lead to red papules, cellulites - like eruption,

ulcerations, acneiform papules, or molluscum - like lesions in patients infected with

HIV.

North American blastomycosis may present as a disseminated maculopapular eruption
in HIV disease.

Systemic coccidioidomycosis may disseminate to the skin, usually as hemorrhagic
papules or nodules

Cutaneous drug eruptions 10%

Sulfonamides may cause urticaria; erythema multiforme; toxic epidermal necrolysis;

and systemic reactions, including fever, leukopenia, thrombocytopenia, hepatitis, and

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