Page 64 - LECTURE NOTES

a) Oral pharyngeal candidasis

b) Oral hairy leukoplakia Epstein-Barr virus (EBV) has been implicated in the
pathogenesis of oral hairy leukoplakia. Oral hairy leukoplakia, which is characterized

by filiform white papules localized on the sides of the tongue, may develop in patients
infected with HIV. Oral hairy leukoplakia has no malignant potential, but it may be the

initial sign of progressive immunosuppression. White plaques may be confused with

oral candidiasis, lichen planus, and geographic tongue.

c) Eosinophilic folliculitis manifests as an idiopathic, highly pruritic, papulopustular

eruption of sterile pustules around hair follicles involving the face, the neck, the trunk,
and the extremities.

d) Herpes ulcer – chronic herpes simplex ulcer More than 1 month

Chronic perianal and perioral herpetic ulcers caused by HSV and disseminated CMV
infection. Recurrent oral and anogenital HSV is common in patients infected with HIV,

and it may lead to chronic ulcerations. In pediatric patients, herpes simplex stomatitis

is more common than varicella zoster virus (VZV), and it may become chronic and
ulcerative.

e) Cytomegalovirus infection

f) Molluscum contagiosum (MC) in adults.
Usually occurs in children, but with HIV it can occur in adults. Molluscum contagiosum

can become confluent and giant. MC nodules can occur with HIV.

g) Bacillary angiomatosis, which is caused by Bartonella henselae and rarely by
Bartonella quintana, is usually manifested by red papules and nodules

Skin disorders at any stage of HIV

Bacterial infections

Impetigo and folliculitis may be recurrent and persistent in HIV disease, particularly in

children.

58