Page 62 - LECTURE NOTES

1- Seroconversion illness: - Acute primary HIV infection may lead to a transient,
generalized, morbilliform eruption on the trunk and the arms. Some 25% will have

exanthema
2- Skin conditions at early and intermediate stage of the disease With the onset of

immunosuppression, skin changes are nonspecific such as common disorders with
atypical clinical features, including recurrent varicella zoster, numerous hyperkeratotic

warts, treatment-resistant seborrhoeic dermatitis, and oral hairy leukoplakia

a) Seborrhoeic dermatitis 85%
seborrheic dermatitis–like eruptions are observed in 85% of patients with AIDS. It may

be the initial cutaneous manifestation of HIV disease. The eruption, which is

characterized by widespread inflammatory and hyperkeratotic lesions in seborrhoeic
areas, may progress to erythroderma in some patients.

Seborrheic dermatitis may be increased in patients with AIDS-associated dementia or

CNS disease.

The immune alterations caused by HIV infection may lead to psoriasis and Reiter

syndrome. In some instances, pre-existing psoriasis may become more severe with
disseminated plaques and pustules.

b. Pityriasis rosea may accompany HIV disease with extensive erythematous
plaques skin lesion with history of herald patches. They can have repeated episodes

of pityriasis rosea.

c) Scabies can be found in all forms of HIV. Classical scabies occurs commonly with

HIV.
Norwegian (crusted) Scabies Atypical scabies which is characterized by wide

spread hyperkeratotic plaque occurs on palms and soles, scaly maculopapular
eruption or crusted can occur in classical sites but can also be generalized involving

face and all parts of the body

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