Page 58 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

P. 58

Herzog 1999 (Continued)

motion abnormality was unchanged with stress and all other segments became
hyperdynamic, the DSE result was classiﬁed as a baseline regional wall motion
abnormality with no inducible ischaemia.

Follow-up Patients were followed up for a mean of 22.5 ± 10.1 months.

Notes
Table of Methodological Quality

Item Authors’ judgement Description
Representative spectrum? Yes Patients referred for kidney transplantation
All tests evaluation.

Acceptable reference standard? Yes Coronary angiography with a reference
All tests standard threshold of ≥ 70% stenosis

Acceptable delay between tests? Yes 47 patients had angiography within 2
All tests weeks after DSE (median, 2 days; mean,
12.4 ± 41 days); three patients had angio-
graphic studies at 69, 85, and 280 days af-
ter DSE (angiography was delayed wound
infection (1 patient) and psychosocial rea-
sons (2 patients)

Partial veriﬁcation avoided? Yes All participants who underwent the index
All tests test received the reference standard test

Differential veriﬁcation avoided? Yes Disease status (CAD) diagnosed by coro-
All tests nary angiography.

Incorporation avoided? Yes Disease status (CAD) diagnosed by coro-
All tests nary angiography.

Reference standard results blinded? Yes All lesions occurring in the major coronary
All tests artery segments or their proximal branches
were visually identiﬁed, and an initial qual-
itative assessment made by a skilled reader
blinded to all clinical data
Index test results blinded? Yes All DSEstudieswere analysedindigital for-
All tests mat independently by three echocardiogra-
phers blinded to angiographic data

Relevant clinical information? Yes Relevant clinical information was provided
All tests regarding the performance and analysis of
both the index and reference tests

53 54 55 56 57 58 59 60 61 62 63