Page 56 - Cardiac testing for coronary artery disease in potential kidney transplant recipients
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Gowdak 2010  (Continued)



                 Study design                   Cross sectional study.

                 Target condition and reference standard(s) Coronary artery stenosis measured by coronary angiography
                                                  • Criterion for positive test results was ≥ 70% reduction in cross sectional area.

                 Index and comparator tests     SPECT+ Sestamibi cardiac scintigraphy
                                                  • Pharmacological stress induced by dipyridamole.

                 Follow-up                      Data not available.

                 Notes                          Data obtained from poster presented at the European Society of Cardiology conference
                                                in 2010 http://spo.escardio.org/AbstractDetails.aspx?id=91377

                 Table of Methodological Quality

                 Item                           Authors’ judgement             Description

                 Representative spectrum?       Yes                            Patients with DM who were candidates for
                 All tests                                                     kidney transplant.

                 Acceptable reference standard?  Yes                           Coronary angiography with a reference
                 All tests                                                     standard threshold of ≥ 70% stenosis

                 Acceptable delay between tests?  Unclear                      Not reported.
                 All tests

                 Partial verification avoided?   Yes                            All patients underwent coronary angiogra-
                 All tests                                                     phy.

                 Differential verification avoided?  Yes                        Disease status (CAD) diagnosed by coro-
                 All tests                                                     nary angiography.

                 Incorporation avoided?         Yes                            Disease status (CAD) diagnosed by coro-
                 All tests                                                     nary angiography.


                 Reference standard results blinded?  Unclear                  Not reported.
                 All tests

                 Index test results blinded?    Unclear                        Not reported.
                 All tests

                 Relevant clinical information?  Yes                           Relevant clinical information was provided
                 All tests                                                     regarding the performance and analysis of
                                                                               both the index and reference tests

                 Uninterpretable results reported?  Yes                        No uninterpretable results present.
                 All tests



                Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review)  54
                Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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