Page 501 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.2. Comparison between watchful waiting and radical prostatectomy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
men, and did not reply moderate): RR=0.7 (0.4,
validated in a to all 1.2)
“small pilot questions] Self-assessed QoL (low to
study”); trait moderate): RR=1.0 (0.6,
measure from 1.6)
the Speilberger
State-Trait Last 6 mo; 4-5 yr post
Anxiety randomization
Inventory; Anxiety (moderate or high):
Center for RR=1.2 (0.6, 2.4)
Epidemiological Depressed mood (moderate
Studies or high): RR=1.5 (1.0, 2.6)
Measure of Sense of well-being (low or
Depression; moderate): RR=1.2 (0.7,
psychological 2.1)
symptoms Self-assessed QoL (low to
(anxiety, moderate): RR=1.0 (0.7,
depressed 1.6)
mood) on 7-
point VAS Last 6 mo; 6-8 yr post
randomization
Anxiety (moderate or high):
RR=0.6 (0.3, 1.1)
Depressed mood (moderate
or high): RR=0.8 (0.5, 1.3)
Sense of well-being (low or
moderate): RR=1.0 (0.6,
1.6)
Self-assessed QoL (low to
moderate): RR=0.8 (0.5,
1.1)

[RR>1 indicates that a
psychological symptom was
more common in the RP
arm]

C-168