Page 497 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.2. Comparison between watchful waiting and radical prostatectomy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
Last 6 mo; 6-8 yr post
randomization
Erectile dysfunction: RR=1.5
(1.2-2.0)
Weak urinary stream:
RR=0.5 (0.3-0.9)
Urinary incontinence:
RR=2.3 (1.3-3.9)
Fecal leakage: NR

[RR>1 indicates that
symptoms were more
common in the RP arm]
Elliott 218 CaPSURE RP vs. WW Treatment for Median 2.7 RP: 3310 HR 10.44 (3.28, 33.27), Age at treatment, clinical
2007 urethral yr (range 3 WW: 378 p<0.001 T stage, Gleason score,
17570425 stricture* days to PSA at diagnosis,
10.9 yr) clinical risk stratification,
Retrospective BMI, urinary condition
cohort history, comorbidity
count, race, marital
status, education,
household income

C-166