Page 432 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 432

Appendix Table C3.2. KQ3 multivariable analyses (continued)
                                            Author          Factors       Data source      Duration      Analyzed         Population         WW/AS          Methods          Results as described in paper
                                              yr                                                          sample        characteristics  definitions
                                             PMI
                                                                                                                                                                             - ≥2 vs. 0, RR=0.67 (CI 0.54,
                                                                                                                                                                           0.83)

                                                                                                                                                                           compared to RT + ADT
                                                                                                                                                                           1. Age, 0.90 (CI 0.90-0.91);
                                                                                                                                                                           P<0.001
                                                                                                                                                                           2. Black vs. white, RR 0.39 (CI
                                                                                                                                                                           0.31-0.50)
                                                                                                                                                                           3. Urban vs. rural, RT RR 1.48 (CI
                                                                                                                                                                           1.18-1.85)
                                                                                                                                                                           4. SES highest vs lowest quintile,
                                                                                                                                                                           RT RR=1.52 (CI 1.26-1.84)
                                                                                                                                                                           5. Grade poor vs. well
                                                                                                                                                                           differentiated, RT RR=2.34 (CI
                                                                                                                                                                           1.78-3.08)
                                                                                                                                                                           6. Comorbidity 2+ vs. 0, RR=0.80
                                                                                                                                                                           (CI 0.67-0.96)
                                                                                                                                                                           7. Comorbidity,
                                                                                                                                                                             - 1 vs. 0, RR=1.11 (CI 0.96, 1.28)
                                                                                                                                                                             - ≥2 vs. 0, RR=0.67 (CI 0.54,
                                                                                                                                                                           0.83)

                                                                                                                                                                           Additional information is provided
                                                                                                                                                                           in Table 2 of the paper for the
                                                                                                                                                                           comparison of ADT monotherapy
                                                                                                                                                                           vs. WW.

                                                                                                                                                                           All estimates were adjusted for
                                                                                                                                                                           SEER region.





















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