Page 428 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 428

Appendix Table C3.2. KQ3 multivariable analyses (continued)
                                            Author          Factors       Data source      Duration      Analyzed         Population         WW/AS          Methods          Results as described in paper
                                              yr                                                          sample        characteristics  definitions
                                             PMI
                                                                                                                                                                           3. Grade, differentiation,
                                                                                                                                                                             - moderate vs. well differentiated,
                                                                                                                                                                           OR=0.3 (CI 0.2, 0.3)
                                                                                                                                                                             - poorly/undifferentiated vs. well
                                                                                                                                                                           differentiated, OR=0.1 (CI 0.1,
                                                                                                                                                                           0.12)
                                                                                                                                                                             - unknown vs. well differentiated,
                                                                                                                                                                           OR=0.4 (CI 0.4, 0.5)
                                                                                                                                                                           4. Life expectancy, <10 yr vs.
                                                                                                                                                                           ≥10y, OR=1.4 (CI 1.3-1.6)
                                                                                                                                                                           5. Age at dx, per yr, OR=1.1 (CI
                                                                                                                                                                           1.07, 1.09)
                                                                                                                                                                           6. Comorbidity, specific conditions,
                                                                                                                                                                             - CHF vs. not, OR=1.4 (CI 1.2,
                                                                                                                                                                           1.6)
                                                                                                                                                                             - COPD vs. not, OR=1.4 (CI 1.2,
                                                                                                                                                                           1.5)
                                                                                                                                                                             - dementia vs. not, OR=2.0 (CI
                                                                                                                                                                           1.4, 3.0)
                                                                                                                                                                           7. Mean inpatient comorbidity
                                                                                                                                                                           index, per unit, OR=1.9 (CI 1.5,
                                                                                                                                                                           2.4)
                                                                                                                                                                           8. Mean outpatient comorbidity
                                                                                                                                                                           index, per unit, OR=1.3 (CI 1.0,
                                                                                                                                                                           1.6)
                                                                                                                                                                           9. Marital status,
                                                                                                                                                                             - single vs. married, OR=1.5 (CI
                                                                                                                                                                           1.4, 1.4)  -
                                                                                                                                                                           10. Income, median census tract
                                                                                                                                                                           income per yr,
                                                                                                                                                                             - <30,000 vs. ≥40,000, OR=1.1
                                                                                                                                                                           (CI 1.03, 1.2)
                                                                                                                                                                             - 30,000 to 39,000 vs. ≥40,000,
                                                                                                                                                                           OR=1.1 (CI 1.03, 1.2)
                                                                                                                                                                           11. Education, % of residents in
                                                                                                                                                                           census tract with less than high
                                                                                                                                                                           school education,
                                                                                                                                                                             - 20-29.99 vs. <20, OR=1.1 (CI
                                                                                                                                                                           1.1, 1.2)




                                                                                                                        C-132
   423   424   425   426   427   428   429   430   431   432   433