Page 433 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C3.2. KQ3 multivariable analyses (continued)
 Author   Factors   Data source   Duration   Analyzed   Population   WW/AS   Methods   Results as described in paper
 yr   sample   characteristics  definitions
 PMI
                                                   - ≥2 vs. 0, RR=0.67 (CI 0.54,
                                                 0.83)

                                                 compared to RT + ADT
                                                 1. Age, 0.90 (CI 0.90-0.91);
                                                 P<0.001
                                                 2. Black vs. white, RR 0.39 (CI
                                                 0.31-0.50)
                                                 3. Urban vs. rural, RT RR 1.48 (CI
                                                 1.18-1.85)
                                                 4. SES highest vs lowest quintile,
                                                 RT RR=1.52 (CI 1.26-1.84)
                                                 5. Grade poor vs. well
                                                 differentiated, RT RR=2.34 (CI
                                                 1.78-3.08)
                                                 6. Comorbidity 2+ vs. 0, RR=0.80
                                                 (CI 0.67-0.96)
                                                 7. Comorbidity,
                                                   - 1 vs. 0, RR=1.11 (CI 0.96, 1.28)
                                                   - ≥2 vs. 0, RR=0.67 (CI 0.54,
                                                 0.83)

                                                 Additional information is provided
                                                 in Table 2 of the paper for the
                                                 comparison of ADT monotherapy
                                                 vs. WW.

                                                 All estimates were adjusted for
                                                 SEER region.





















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