Page 409 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C3.1 Studies on offer, acceptance, and adherence of active surveillance (continued)
Factors examined Author Study approach AS/WW definitions Findings Issues
Year
PMID
Adherence to Zietman 186 Retrospective study of 198 men Surveillance/WW: no • 81% believed that treatment • Nonvalidated
AS (actually 2001 with early stage disease on WW in primary treatment with was desired by the physicians, telephone survey (not
receiving active 11586206 2 institutions, 63 of whom ultimately radiation, which was the primary cause of described)
treatment); received treatment; 53 of them prostatectomy or the change in plan. • Retrospective
clinical factors responded to an 8-point phone androgen deprivation; • In contrast, MD notes definition of WW
(perception of questionnaire (10 did not respond DRE & PSA q4-6 mo revealed that for only 24% was • Only surveyed those
physician because they had died, were too (retrospective study) there documentation that MDs who received therapy
advice) infirm or too elderly) advocated therapy due to • Survey response rate
clinical or biochemical evidence 84%
of tumor progression. • Did not report on full
o 71% had PSA increase survey results, including
only and 11% had no the intended purposes of
progression evidence influences that affected
• Physicians more often decision
perceived that treatment was
initiated by patients (in abstract
conclusions only)

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