Page 414 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C3.2. KQ3 multivariable analyses

                                            Author          Factors       Data source      Duration      Analyzed         Population         WW/AS          Methods          Results as described in paper
                                              yr                                                          sample        characteristics  definitions
                                             PMI
                                        Receipt of
                                        AS/WW
                                        versus
                                        alternative
                                        treatments
                                              66
                                        Harlan            Clinical,      CaPSURE           1989-       5365             Localized          No active      Logistic         1. low vs. high risk (D’Amico),
                                        2003              social,                          2000                         prostate ca        treatment      regression       OR=5.1 (CI 3.8, 6.9)
                                        14532780          insurance                                                                                       predicts WW      2. >75 yr vs. <65 yr, OR=14.3 (CI
                                                                                                                                                          vs. active       9.1, 22.5)
                                                                                                                                                          treatment        3. comorbidity score >1 vs. 0-1,
                                                                                                                                                                           OR=1.43 (CI 1.1, 1.8)
                                                                                                                                                                           4. private ins. vs. Medicare,
                                                                                                                                                                           OR=0.7 (CI 0.5, 1.0)

                                                                                                                                                                           NS: academic vs. community;
                                                                                                                                                                           black vs. white; education; income;
                                                                                                                                                                           in relationship
                                        Meng 179          Clinical,      CaPSURE           1989-       6074             Localized          Not            Multinomial      1. ≥70 yr vs. <70 yr, OR=49.4 (CI
                                        2005              insurance                        2002                         prostate ca –      explicitly     logistic         13.2, 185.4)
                                        15821485                                                                        high risk          provided       regression       2. PSA >20 vs. ≤10, OR=4.6 (CI
                                                                                                                                                          WW vs. RP        1.7, 12.8)
                                                                                                                                                                           3. Medicare + suppl vs. private,
                                                                                                                                                                           OR=9.2 (CI 2.1, 39.2)

                                                                                                                                                                           NS: Gleason, T stage,
                                                                                                                                                                           comorbidities, marital status

























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