Page 103 - Screening for Cervical Cancer: Systematic Evidence Review

Appendix C. Evidence Tables

Evidence Table 1A. Screening Among Older Women (cont’d)

Screening Outcomes & Quality
Participants Program Measures Relevant Results Considerations
N = 40,536 No systematic Primary AGE: Denom=2
women with screening outcome = CIN Incidence Attrition=2
58,271 Paps; program in 1-cancer on Cases Cases Total Indications=2
no prior place; cytology CIN 1-2 CIN 3 N Interval=2
abnormal centralized ≤ 19 43 1 4,962 Age=2
cytology recall for follow- (No histology 20-29 203 21 18,531 Relevance=1
30-39 96 27 13,761
including up of abnormal based data) 40-49 43 13 9,955 Standard=0
smears with Paps only 50-59 22 12 5,370 Score=11
evidence of 60-69 10 7 3,568
HPV or Herpes 70 10 9 2,124 Grade=Fair
virus
ORs* CIN 3 & Cancer Among Older
Age 13-100, Women (95%CI)
mean age: 36 Age CIN 3 Cancer
50-59 1.0 (ref) 1.0 (ref)
60-69 0.6 (0.2, 1.4) 2.5 (0.7, 9.7)
≥ 70 0.8 (0.2, 0.8) 1.9 (0.4, 8.1)
* Adjusted for time since last smear

INTERVAL:
(months) OR^ (95%CI)
First 1.0 (ref) 1.0 (ref)
12 0.1 (0.0, 0.7) ---
13-35 0.04 (0.0, 0.2) 0.04 (0.0, 0.3)
36-59 0.12 (0.0, 0.4) 0.1 (0.1, 0.8)
60 0.26 (0.1, 0.7) 0.5 (0.2, 1.6)
^ Adjusted for age

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