Page 272 - Pagetit

INDEX

Index

Note: bold page numbers denote material in figures, tables and boxes.

Acamprosate, and alcohol abuse 72
Acetylcholine 33
Action potential 29, 30
ADHD, see Attention deficit hyperactivity disorder
Adoption studies 127
Alcohol dehydrogenase 135
Alcohol use 69–73, 107
adaptations to prolonged use 72
behavioural effects 69–70
and depression 183–184
flushing/sensitivity response 134
genetic studies 132–136
ALDH2 134–135
combined risk with other psychoactive substances 138–147
CYP2E1 135–136, 139
linkage 133–134
twinning 132–133
mechanism of action 70
prevalence of abuse 169
abstention/consumption rates 8
mortality 17
selected countries 5–8, 6
schizophrenia 176
and smoking, linkage studies 139
tolerance and withdrawal 70–72
treatment of dependence 72–73
Alcohol-metabolizing enzyme CYP2E1 135–136, 139
Aldehyde dehydrogenase 134
Amphetamines 93–96, 108
acute vs chronic use 175–176
adaptations to prolonged use 96
dependence, and schizophrenia 174–175
development of tolerance 54

251

Index 251 19.1.2004, 11:52