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Viral Tropism
Refers to which type of coreceptor HIV uses when binding to a cell
during infection. HIV can bind to the CXCR4 coreceptor (X4-tropic)
or to the CCR5 coreceptor (R5-tropic) on a cell surface. Although
the virus often prefers one coreceptor to the other, it also can be
dual/mixed-tropic HIV that can bind to either coreceptor. Viral
tropism may switch, or change from preference of one coreceptor
to the other, during the course of an HIV infection.
See Also: CCR5
CXCR4
Viremia
The presence of virus in the bloodstream.
Viricide
Any substance that can destroy or inactivate a virus.
Virion
A mature virus particle that exists freely outside a host cell.
Virologic Control
See: Viral Suppression
Virologic Failure
Inability of anti-HIV drug treatment to reduce viral load or to maintain
suppression of viral load. Virologic failure is the most common type
of treatment failure and may lead to immunologic and clinical failure.
See Also: Immunologic Failure
Clinical Failure
Viral Load (VL)
Virology V
The study of viruses and viral disease.
HIV/AIDS Glossary 141