Page 108 - 78 glossary of hivaids-related terms_opt

Phase IV Trial
A clinical study that occurs after a drug has been approved by
the Food and Drug Administration (FDA) to determine long-term
safety and effectiveness. Sometimes referred to as a post-marketing
study. This trial phase recruits the largest population of patients
to gain additional information about the drug’s risks, benefits, and
optimal use.

Phenotypic Assay
A laboratory test that determines by direct experiment whether a
particular strain of HIV is resistant to anti-HIV drugs. This is different
from a genotypic assay, which uses an indirect method to find out
if a particular strain of HIV has specific genetic mutations that are
associated with drug resistance.
See Also: Resistance Testing
Genotypic Assay

Photosensitivity
Increased sensitivity of skin to sunlight or ultraviolet light.
Photosensitivity commonly causes reddening and blistering of
the skin and in time increases a person’s risk of skin cancer.
Photosensitivity may occur as a side effect of some drugs or as
P a result of HIV infection.

PHS
See: Public Health Service

PI
See: Protease Inhibitor

PID
See: Pelvic Inflammatory Disease

Pill Burden
The number and schedule of pills taken each day in a particular
anti-HIV drug regimen. A high pill burden may lead to decreased

106 HIV/AIDS Glossary