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Peptic Ulcer Disease in Children 375

Key Summary Points
1. Peptic ulcer disease in children is being recognized 5. Newborns and infants tend to present with acute complications
increasingly worldwide, including developing countries. such as haemorrhage or perforation.
2. A high index of suspicion is necessary to distinguish PUD in 6. Oesophagogastroduodenoscopy is the main diagnostic
children from other causes of abdominal pain. investigation and is safe in the paediatric age group.
3. Helicobacter pylori is an important aetiological factor in PUD 7. The mainstay of management of paediatric PUD is medical,
in children. consisting of a combination of PPI, sucralfate, or bismuth with
4. Peptic ulcer may present with such complications as two antibiotics.
haemorrhage, perforation, and gastric outlet obstruction, even 8. Surgery is indicated only for complications such as uncontrolled
in the absence of pain. haemorrhage, perforation with peritonitis, and gastric outlet obstruction.

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