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370  Infantile Hypertrophic Pyloric Stenosis

        the wound and elevated to lift the transverse colon. This manoeuvre   Postoperative Management
        enables the surgeon to identify the antrum of the stomach. The lower   Postoperative  nasogastric  decompression  is  not  necessary  unless  the
        third of the stomach is then gently elevated using moist gauze to   mucosa has been entered and repaired. Several feeding schedules have
        deliver the pyloric mass into the wound (Figure 59.3).   been advocated after surgery. Traditional structured feeding regimens
        2. A vertical incision is then made into the mid anterior surface through   as opposed to more rapid initiation and advancing feeding schedules are
        the serosa and superficial muscularis, beginning about 1–2 mm from   probably unnecessary. Feedings are begun 4 to 6 hours after operation,
        the pyloroduodenal junction to a point 0.5 cm into the lower antrum.   normally  with  low-volume  balanced  electrolyte  or  dextrose  solution
                                                               initially, rapidly advanced to full feeds of formula over the next 12- to
        3. The underlying firm fibres are then divided using blunt dissection
                                                               24-hour period. If the patient vomits, which is common after this pro-
        with a clamp, rounded end of a scalpel blade, or special Benson’s
                                                               cedure, the same volume feed that caused the emesis can be repeated.
        pyloromyotomy spreader. Special care is taken to prevent mucosal
                                                               The patient is usually discharged the day after operation.
        perforation, especially at the lower end of the incision. Upward
        protrusion of the gastric mucosa indicates relief of the obstruction   Surgical Complications
        (Figures 59.4 and 59.5).                               Intraoperative risks include bleeding, infection, and mucosal perforation.
          Mucosal  perforation  usually  occurs  at  the  duodenal  end  and  is   Postoperative  complications  include  wound  infection  and  dehiscence  in
        indicated by the appearance of bilious fluid. When this occurs, repair   about 1%. Persistent vomiting beyond 48 hours, thought to be due to gastric
        is done by using interrupted fine monofilament long-term absorbable   atony,  occurs  in  about  3%.  Unrecognized  perforation  during  pyloromy-
        sutures placed transversely and covered with omentum. If the closure of   otomy is a serious but rare problem demanding immediate reoperation.
        the mucosal perforation compromises the pyloromyotomy, which rarely
        happens, a fresh pyloromyotomy is done at about 45°–90° of the first        Outcome
        incision. Air is then instilled through the NGT to check the integrity of   The majority of infants go on to make a full recovery postoperatively
        the duodenal mucosa.                                   and need no further medical input. After a surgical pyloromyotomy, the
            Use  of  a  laparoscopic  approach  is  increasing,  with  evidence   pyloric muscle subsides to a normal size and, when viewed during sub-
        supporting its benefits emerging. 18,19  A recent study has shown a safe   sequent operations, is usually visible only as a fine line over the pylorus
        alternative with a decreased time to full feeds postoperatively. 20  at the site of the myotomy.
                                                                 Incomplete pyloromyotomy may occur, but it is difficult to diagnose in the
                                                               early postoperative phase. Imaging studies done postoperatively are difficult
                                                               to interpret and usually not helpful. If complete gastric-outlet obstruction is
                                                               present on a contrast study, repeated pyloromyotomy is necessary.
                                                                 Mortality is rare, but when it occurs, it is usually from fluid and
                                                               electrolyte  depletion  in  infants  presenting  late,  and  inadequately
                                                               corrected electrolyte problems before surgery.
                                                                           Evidence-Based Research
                                                               Evidence on the management of pyloric stenosis in African children is
                                                               rare, so clinicians have to depend on literature from the West, where the
        Figure 59.3: Operative view of pyloric mass.           disease is more frequent. Table 59.1 presents the results of a survey on
                                                               the management of IHPS conducted in the United Kingdom and Ireland.
                                                               Table 59.1: Evidence-based research.
                                                                  Title     Surgical practice for infantile hypertrophic pyloric stenosis in
                                                                            the United Kingdom and Ireland—a survey of members of the
                                                                            British Association of Paediatric Surgeons
                                                                  Authors   Mullassery D, Perry D, Goyal A, Jesudason EC, Losty PD
                                                                  Institution  Academic Department of Pediatric Surgery, The Royal
                                                                            Liverpool Children’s Hospital (Alder Hey), University of
                                                                            Liverpool, United Kingdom
                                                                  Reference  J Pediatr Surg 2008; 43:1227–1229
                                                                  Problem   Current practice amongst paediatric surgeons on the
                                                                            management of infantile hypertrophic pyloric stenosis.
                                                                  Outcome/  More than half of the surgeons surveyed used umbilical
        Figure 59.4: Spreading of the divided pyloric muscle.     effect    incision for pyloromyotomy, whereas only 15% do the
                                                                            pyloromyotomy laparoscopically. Fewer than 10% of surgeons
                                                                            surveyed use the classical right upper quadrant incision for
                                                                            pyloromyotomy. The study also showed that about half of the
                                                                            surgeons do not use antiobiotics; however, 70% of those using
                                                                            the umbilical incision use antibiotics. The study concluded that
                                                                            umbilical incision and laparoscopic incisions are benchmarks
                                                                            for surgeons caring for children with infantile hypertrophic
                                                                            pyloric stenosis.
                                                                  Historical   Acknowledging that IHPS may not be a major workload for
                                                                  significance/  the paediatric surgeon practicing in Africa, patients with this
                                                                  comments  condition do come in occasionally, especially in major centres,
                                                                            so paediatric surgeons need to be aware of the current
                                                                            practices amongst paediatric surgeons who care frequently for
                                                                            these patients; hence, the importance of this article. Although
                                                                            there are a lot of variations in the practice, pyloromyotomy
                                                                            through whatever route remains the gold standard for caring
        Figure 59.5: Myotomy with mucosal bulge.                            for these group of patients.
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