Page 61 - Drug Class Review
P. 61
Drug Effectiveness Review Project
Drugs Authors: AD2000 Collaborative Group 38 NHS Executive R&D and Health Authorities in the West Midlands, East Lancashire, Iechyrd Morgannwg, and North Nottingham To determine whether long-term DON treatment produces worthwhile improvements in disability, dependency, behavioral, and psychological symptoms or delay in institutionalism Study design: RCT *Effectiveness trial* Setting: Multi-center (22 memory clinics) placebo donepezil N/A 5 or 10 mg/d 192 weeks 192 weeks 283 282 Community residents referred by treating doctor; DSM-IV diagnosis of AD with or without co-e
Alzheimer Year: 2004 Country: UK Sample size: 565
Final Report Update 1 Efficacy/Effectiveness STUDY: FUNDING: RESEARCH OBJECTIVE: DESIGN: INTERVENTION: Dose: Duration: Sample size: INCLUSION: EXCLUSION: OTHER MEDICATIONS/ INTERVENTIONS ALLOWED: Alzheimer's Drugs
