Page 107 - LECTURE NOTES

Epidemiology

Over 85% of adults have serological evidence of herpes simplex type 1 infection.
Most often acquired asymptomatic in childhood. Occasional primary infection

may manifest as sever gingivostomatitis in small children. Herpes simplex is

may have recurrent infection and self limited attacks, by precipitated fevers, a

viral infection, fatigue, menstruation and others triggering factors such as the sun

and wind.

Genital herpes (type 2) is considered a sexually transmitted infection. It is, a

major concern to health care providers and consumers because of the increasing

prevalence of the disease, which is 400,000 to 500,000 new cases each year

and it also can recur.

Herpes simplex type 2 (Herpes genitals)

It is a viral infection that causes vesicles and bullos lesion on the cervix, vagina

and external genitalia: Herpes simplex virus (HSV-2) appears to be causative

virus in over 80% of genital and perineal lesions and about 20% are HSV- 1.
Usually the virus is killed at room temperature by drying.

Mode of transmission

The disease will transmit sexually and asexually from a wet surface or by self-

inoculation (i.e. touching a cold sore and then touching the genital area).
Generally close human contact with secretions of the oropharynx mucosal

surface, vagina and cervix seems necessary to acquire the infection of herpes

simplex.

Clinical manifestation
¾ Itching which accompanies red and edematous lesion.

¾ Typical lesion is grouped papules and vesicles which later ulcerates and

encrusts in females, The labia is the usual the primary site and possibly

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