Page 119 - 20dynamics of cancer
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104                                                 CHAPTER 6
















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                              Figure 6.3  Distribution of independent lines of progression across various
                              stages, which depends only on n, u, and t. Here, n = 10 and t = 80. The
                              stage n = 10 is excluded; that stage causes cancer, and the distributions here
                              show the stages among individuals who have not had cancer. The panels from
                              top to bottom correspond to the parameters for the four curves from top to bot-
                              tom in Figure 6.1a, plus a fifth value of u = 0.1209, corresponding to m = 0.5
                              and L = 1, for the distribution in the bottom panel of this figure.
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