Page 320 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 320

Appendix Table C1.14. Treatment characteristics—changes in treatment patterns over time (continued)
                                        Author                Database         Treatment          1980-     1985-89        1990-94        1995-     2000-04      2005-     Statistical          Notes
                                        Year                                                      84                                      99                     10        analysis
                                        PMID
                                                              SEER             EM/ADT                       NR                                      43.6%                  P=0.008              The historical
                                                                               RP                           17%                                     10.6%                  (overall chi-        cohort (1988-
                                                                               RT                           31%                                     45.9%                  square test for      90) was used
                                                                               [lower-risk]                 (1988-90)                               (2001)                 2000-02)             for comparison
                                                                                                                                                                                                of treatment
                                                                                                                                                                                                patterns
                                                                                                                                                                                                among lower-
                                                                                                                                                                                                risk patients
                                                                                                                                                                                                only.

                                                                                                                                                                                                Lower-risk
                                                                                                                                                                                                patients were
                                                                                                                                                                                                those with
                                                                                                                                                                                                well-diff.
                                                                                                                                                                                                tumors
                                                                                                                                                                                                regardless of
                                                                                                                                                                                                age or those
                                                                                                                                                                                                with
                                                                                                                                                                                                moderately
                                                                                                                                                                                                diff. tumors
                                                                                                                                                                                                aged ≥70 yr.



































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