Page 319 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C1.14. Treatment characteristics—changes in treatment patterns over time (continued)
Author Database Treatment 1980- 1985-89 1990-94 1995- 2000-04 2005- Statistical Notes
Year 84 99 10 analysis
PMID
36
Harlan SEER RP 11.0% 32.3% P<0.001 Additional
1995 RT 27.0% 29.7% (chi-square test) information is
7799048 Other NR NR presented in
(including, ADT (1984) (1991) Figures 1-4 of
or careful the paper
observation (1984-91).
with therapy
reserved for
clinical
progression)
Age-adjusted
proportions for
initial Tx (within
4 mo of
diagnosis)
41
Miller SEER EM/ADT 20.0% P=0.042 Higher-risk
a
2006 RP 43.1% (overall chi- patients were
16912266 RT 36.9% square test for those with
[higher-risk] (2001) 2000-02) poorly diff.
tumors
regardless of
age or those
with
moderately
diff. tumors
aged <70 yr.

a The study reported data for the period 2000-02, which fits entirely in one of our table’s 5 yr bins. We extracted data for the midpoint of the study period (i.e.,
2001) along with the p-value from tests comparing the frequency of treatments across all 3 study years. Readers are referred to the full text of the paper for
additional information.

C-77