Page 292 - AIDSBK23C

Page 292

Table 4 - Definitive Diagnostic Techniques for Diseases Indicative of AIDS

Indicator Disease Microscopy Microbiologic Serum Clinical
for AIDS (cytology, histology) Culture Serology Criteria

Candidiasis H&E,PAS,GMS - - Gross Appearance

Cervical cancer H&E - - -

Coccidioides immitis H&E,PAS,GMS Fungal Antigen -

Cryptococcus neoformans H&E,PAS,GMS Fungal Antigen -

Cryptosporidium H&E,AFB - - -

Cytomegalovirus H&E,IPX Viral Antigen -

Encephalopathy, HIV - - - Clinical Features

Herpes simplex virus H&E,IPX Viral Antigen -

Histoplasma capsulatum H&E,PAS,GMS Fungal Antigen -

HIV wasting syndrome - - - Clinical Features

Isosporiasis H&E,AFB - - -

Kaposi's sarcoma H&E - - -

LIP H&E - - -

Malignant Lymphoma H&E,IPX - - -

Mycobacteria - Mycobacterial - -

PML H&E,IPX - - -

Pneumocystis pneumonia GMS,Giemsa,IPX - - -

Pneumonia, recurrent - Routine - Clinical Features

Salmonellosis - Routine - -

Toxoplasma gondii H&E,IPX - - -

Key: H&E=routine hematoxylin and eosin stain; IPX=immunohistochemical method with specific monoclonal
antibody; GMS=Gomori methenamine silver stain; PAS=periodic acid-Schiff stain; AFB=Ziehl-Neelsen or Kinyoun
acid fast stain; Giemsa=Giemsa stain; LIP=lymphoid interstitial pneumonitis; PML=progressive multifocal
leukoencephalopathy