Page 153 - Screening for Cervical Cancer: Systematic Evidence Review
P. 153

Chapter I.  Introduction










                                         Invasive   Carcinoma            V









                                                           In situ   Carcinoma



                                                       Grade 3
                                                High Grade (HSIL)  Cervical Intraepithelial Neoplasia (CIN)   Severe   Dysplasia   IV
                                            Squamous Intraepithelial Lesion (SIL)
                                  Epithelial Cell Abnormalities








                                                       Grade 2   Moderate   Dysplasia









                                                Low Grade (LSIL)   Condyloma   Grade 1      Dysplasia  Mild  III


                      Figure 1.  Map of Cervical Cytology Classification Schemes










                                            ASCUS*








                           Benign   Cellular   Changes   Infection   Reactive   Repair      – – – –   Atypia  II







                           Within   Normal   Limits   Normal         I      * ASCUS, Atypical squamous cells of uncertain significance.






                               Classification   System   The Bethesda   System 28       Richart 29    Reagan 30    WHO  Nyirjesy 31    Source:  McCrory et al., 1999 32












                                                                                  19
   148   149   150   151   152   153   154   155   156   157   158