Page 156 - Screening for Cervical Cancer: Systematic Evidence Review
P. 156

Chapter I.  Introduction



                   Table 1.      Technical Characteristics of HPV Testing Methods
                                                                                                   Suitable for
                                                      Low            High          Complex            High
                                                   Sensitivity    Sensitivity   Execution/Low     Throughput/
                                                      and            and         Potential for    Amenable to
                   Test Technique                  Specificity    Specificity    Automation        Automation
                   Southern blot                       √                              √
                   In situ hybridisation protocols*    √                              √
                   Dot blot procedures                 √
                   Hybrid Capture I                    √                              √
                   Hybrid Capture II                                   √                                √
                   PCR                                                 √
                   Consensus PCR  †                                    √                                √
                                                     21
                   Source:  Adapted from Cuzick et al., 1999.
                   * Includes Flourescent In Situ Hybridisation (FISH).
                   †PCR, polymerase chain reaction.























































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