Page 148 - Screening for Cervical Cancer: Systematic Evidence Review
P. 148

Appendix C.  Evidence Tables



               Evidence Table 3B.  Performance of HPV Testing for Triage (cont'd)

                 Source: Author,       Study Design &
                      Year             Characteristics          Interventions        Location & Time Period
                               66
               Bollen et al., 1997   Diagnostic test evaluation  HPV testing of abnormal  Amsterdam
                                  among abnormal Paps;     Paps using two tests:   1994-1995
                                  screening for HPV and    CPI/IIG primer pair and
                                  type compared with       MY09/11 polymerase
                                  colpsocopy/histology     chain reaction using
                                                           SHARP signal system
                                  Pap negatives not verified,  and probe sets A & B
                                  HPV negatives verified
                                                           Colposcopy and histology






















               Sigurdsson et al,   Descriptive study of HPV   1) Cytologic and     Population based screening
               1997 67            expression in 358        histopathologic findings,   program, Iceland
                                  abnormal smears referred  2) Presence and amount  1994
                                  for colposcopy.          of HPV by hybrid capture
                                                           and PCR,
                                                           3) Presence of HPV in
                                  Pap negatives not verified  swabs and biopsies,
                                                           4) Distribution of HPV
                                                           type by cyto- and
                                                           histopathological findings


























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